MN Healthcare

Quinine sulphate is an antimalarial medicine used mainly for treating uncomplicated malaria caused by Plasmodium falciparum.

Composition
Quinine Sulphate IP – strength varies by brand (commonly 200 mg or 300 mg).
Plus standard tablet excipients.

Class
Antimalarial (Cinchona alkaloid)

Used for
• Treatment of malaria, especially chloroquine-resistant P. falciparum
• Nocturnal leg cramps (not routinely recommended)

How it works
Interferes with malaria parasite growth within red blood cells.

Dose
Dose depends on strength and doctor’s prescription. Typically given every 8 hours for malaria treatment.

Shelf life
Usually 24–36 months.

Storage
Store below 25°C
Keep tablets in original strip
Protect from moisture and direct light

1. What It Is

Artesunate 200 mg is a fast-acting antimalarial medicine used for the treatment of acute uncomplicated malaria, particularly caused by Plasmodium falciparum.
It is often used as part of ACT (Artemisinin-based Combination Therapy).

2. Composition

• Active Ingredient: Artesunate IP – 200 mg per tablet

• Excipients: Starch, lactose, microcrystalline cellulose, magnesium stearate, povidone (brand may vary)

3. Dosage Form

• Oral tablet

4. Prescribed For

Artesunate 200 mg is prescribed for:

✔ Acute uncomplicated malaria
✔ Falciparum malaria
✔ Mixed infections (when falciparum involvement suspected)

Usually given with another antimalarial to avoid resistance (e.g., Sulfadoxine-Pyrimethamine, Mefloquine, or Amodiaquine).

5. How It Works

Artesunate rapidly kills malaria parasites in the blood by producing free radicals that damage parasite proteins, leading to quick symptom relief.

6. Ideal For

• Adults and children (doctor-supervised)
  Dose is adjusted by body weight.

7. Packaging Type

Common formats:

• Blister pack (1×4 or 1×6 tablets)

• 10×10 blister box

8. Shelf Life

✔ 24 months (standard in most brands)

9. Prescription Status

✔ Prescription-only (Rx)
Not for over-the-counter use.

Generic Name

Artesunate

Strength

50 mg

Dosage Form

Oral tablet

Description

Artesunate 50 mg is a fast-acting antimalarial medicine used for the treatment of acute uncomplicated malaria, especially caused by Plasmodium falciparum.
It belongs to the artemisinin derivatives, known for rapidly reducing malaria parasite counts in the blood.

Artesunate is often used as part of Artemisinin-Based Combination Therapy (ACT) to prevent resistance.

Prescribed For / Uses

Artesunate 50 mg is commonly used for:

✔ Uncomplicated malaria (P. falciparum) ✔ Mixed malaria infections ✔ Initial treatment before combination therapy ✔ Cases with chloroquine-resistant malaria

Note: Severe malaria is generally treated with injectable artesunate, not tablets.

How It Works

• Converts to dihydroartemisinin (DHA) inside the body

• Produces free radicals toxic to malaria parasites

• Rapidly kills parasites in the blood

• Brings down fever and symptoms quickly

Packaging Type

Common packaging:

• Blister pack (Alu-Alu or PVC)

• 4 or 10 tablets per strip

(Varies by manufacturer.)

Shelf Life

Typically 24 months (2 years) from manufacturing.

Also Contains (Inactive Excipients)

(Varies by brand)

• Lactose

• Microcrystalline cellulose

• Starch

• Magnesium stearate

• Talc

• Permitted colours / film coating agents

Usage / Application

Personal / Clinical
(Oral antimalarial therapy taken as per doctor’s prescribed regimen)